The
Guggenheimer, et al. Study, 2000
Prevalence rates (per 1,000 persons) for oral mucosal lesions
found in
673 persons (268 controls and 405 insulin-dependent
diabetes mellitus patients
in Pittsburgh, Pennsylvania, i.e. EDC
Study: Pittsburgh Epidemiology of Diabetes
Complications Study).
[32 subjects were less than 20 years of age, 131 were more than 40 years old; about 50% males]
|
Clinical Diagnosis |
# Lesions/1000 Persons |
||
| Controls (n=268) |
IDDM
Patients (n=405) |
P Value | |
Gingivitis, marginal |
90 | 94 | |
|
Migratory glossitis |
34 | 54 | |
|
Aphthous ulcer |
30 | 15 | |
Smooth red tongue (diffuse atrophic glossitis) |
22 | 89 | <.001 |
|
Parotid enlargement |
22 | 30 | |
|
Gingival hyperplasia |
15 | 17 | |
|
Denture stomatitis (denture sore mouth) |
15 | 47 | <.05 |
|
Traumatic ulcer |
11 | 35 | <.05 |
|
Angular cheilitis |
11 | 32 | |
|
Herpes labialis |
7 | 2 | |
|
Lichen planus |
7 | 5 | |
|
Fissured tongue |
4 | 54 | <.0001 |
|
Irritation fibroma |
4 | 25 | <.05 |
Fistulous tract, dental |
4 | 10 | |
|
Epulis fissuratum |
0 | 7 | |
Gingivitis, extensive |
0 | 5 | |
|
Candidiasis, pseudomembranous |
4 | 5 | |
|
Papilloma |
4 | 2 | |
|
Median rhomboid glossitis |
4 | 2 | <.0001 |
|
Total: |
250 |
444 |
<.0001 |
Guggenheimer
J, Moore PA, Rossie, Myers D, et al. Insulin-dependent diabetes mellitus and
oral soft tissue pathologies. I. Prevalence and characteristics of non-candidal
lesions. Oral Surg Oral Med Oral Pathol 2000; 89:563-569.
Guggenheimer J, Moore PA, Rossie, Myers D, et al. Insulin-dependent diabetes
mellitus and oral soft tissue pathologies. II. Prevalence and characteristics of
Candida and candidal lesions. Oral Surg Oral Med Oral Pathol 2000; 89:570-576.